An opinion should be the result of thought, not a substitute for it.
Humility is no substitute for a good personality.
Advertising is the modern substitute for argument; its function is to make the worse appear the better.
The solution is to gradually become free of societal rewards and learn how to substitute for them rewards that are under one's own powers. This is not to say that we should abandon every goal endorsed by society; rather, it means that, in addition to or instead of the goals others use to bribe us with, we develop a set of our own.
Thankfully, persistence is a great substitute for talent.
Substitute 'damn' every time you're inclined to write 'very;' your editor will delete it and the writing will be just as it should be.
Intimate relationships cannot substitute for a life plan. But to have any meaning or viability at all, a life plan must include intimate relationships.
Today's scientists have substituted mathematics for experiments, and they wander off through equation after equation, and eventually build a structure which has no relation to reality.
Dressing up is inevitably a substitute for good ideas. It is no coincidence that technically inept business types are known as "suits."